产品货号:
Z21664
中文名称:
NAIP抗体
英文名称:
Anti-NAIP Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-NAIP Antibody |
| 指标别名 | BIRC1;Birc1a;NAIP;Naip1;NLRB1;psiNAIP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | NAIP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.The immunogen is located within amino acids 1200 - 1250 of NAIP. |
| 计算分子量 | 160kDa |
| 成分 | NAIP Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NAIP Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy.Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR);these BIRs promote protein-protein interactions with various caspases such as caspase-3,-7,and -9 as well as members of the TRAF family of signal molecules.Unlike other IAPs however,NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO,suggesting that NAIP is unique among the IAPs in its regulation of its activity.Finally,although only one human NAIP protein has been identified,other shorter NAIP mRNA transcripts have been reported. |
| Uniprot ID | Q13075 |
| 基因名全称 | NLR family,apoptosis inhibitory protein |
| 蛋白名全称 | NLR family,apoptosis inhibitory protein |
| 推荐稀释比 | NAIP antibody can be used for the detection of NAIP by Western blot at 0.5 to 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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